Schreiber {SemSim}R Documentation

SMIR-binding Proteins

Description

This dataset includes 37 yeast proteins that bind small molecule inhibitors of rapamycin identified by yeast proteome array.

Usage

data(Schreiber)

Format

The format is: chr [1:37] "852215" "852291" "852369" "852514" "851334" ...

Source

Huang, J, Zhu, H, Haggarty, S.J., Spring D.R., Hwang, H., Jin, F., Snyder, M., Schreiber S.L. (2004) Finding new components of the target of rapamycin signaling network through chemical genetics and proteome chips. Proc Natl Acad Sci 101(47): I6594-I6599.

References

Wolting, C., McGlade, C.J., and Tritchler, D. (2006) Cluster analysis of protein array results via similarity of Gene Ontology annotation. BMC Bioinformatics 7:338.

Examples

  data(Schreiber)
  mgeneSim(Schreiber[1:5])

[Package SemSim version 1.4.0 Index]