getCopyNumberScale {VanillaICE} | R Documentation |
We typically assume that after appropriate transformation the distribution of copy number is approximately Gaussian. This function calculates a robust estimate of the spread based on quantiles of the observed copy number distribution across all autosomes.
getCopyNumberScale(object, ...)
object |
Object of class HmmSnpSet or
HmmSnpCopyNumberSet |
... |
additional arguments for subsetting the samples |
A vector of scales with length equal to the number of hidden states (typically 3 or 4)
RB Scharpf et al. (2007), Department of Biostatistics Working Papers, Working Paper 136