normexp.signal {limma}R Documentation

Expected Signal Given Observed Foreground Under Normal+Exp Model

Description

Adjust foreground intensities for observed background using Normal+Exp Model. This function is called by backgroundCorrect and is not normally called directly by the user.

Usage

normexp.signal(mu,sigma,alpha,foreground)

Arguments

mu numeric vector giving expected values for signal
sigma numeric scalar giving standard deviation of background intensities
alpha numeric scaler giving exponential decay rate of foreground intensities
foreground numeric vector of foreground intensities

Details

In general the vector mu is computed conditional on background at each spot.

Value

Numeric vector containing adjusted intensities.

Author(s)

Gordon Smyth

See Also

An overview of background correction functions is given in 04.Background.


[Package limma version 2.2.0 Index]