normInteraction {SLGI} | R Documentation |
Normalize a square matrix of biological interactions according to the number of possible interactions between each biological complex.
normInteraction(data, genename, interactome)
data |
Square Matrix of biological complexes that shares one or more genes(proteins) |
genename |
|
interactome |
Adjacency matrix where row are genes and
columns are cellular organizational units. Each entry has
value 0 or 1, for absence or presence of a gene in a complex, e.g., ScISI |
Square matrix of biological complexes linked by one or more interacting proteins and normalized by the possible number of interactions between each complex.
N. LeMeur
data(Atong) data(ScISIC) data(SGA) SLa2 <- gi2Interactome(Atong, ScISIC) ## Search for synthetic lethal interaction compM <- getInteraction(SLa2, SGA, ScISIC) ## Normalize normIntComplex<- normInteraction(compM$bwMat, SGA, ScISIC)