crosshybFilter {oneChannelGUI}R Documentation

Removing from exon array gene/exon level probe sets characterized by cross hybridization with other transcripts

Description

XHYB field is mainly an indicator of weak assignment between a transcript cluster and the assigned mRNA, suggesting a potential crosshyb, CRSSHYB is a measure of the promiscuity of the probes within a probe set among transcribed sequences. begin{enumerate}

  • 1 unique. All probes in the probe set perfectly match only one sequence in the putatively transcribed array design content. The vast majority of probe sets are unique.
  • 2 similar. All the probes in the probe set perfectly match more than one sequence in the putatively transcribed array design content.
  • 3 mixed. The probes in the probe set either perfectly match or partially match more than one sequence in the putatively transcribed array design content. end{enumerate} XHYB and CRSSHYB are used to remove probe sets characterized by multiple hybridization of exon probes

    Usage

    crosshybFilter()
    

    Author(s)

    Raffaele A Calogero


    [Package oneChannelGUI version 1.8.10 Index]